Those with a family history, i.e. first degree relative, have 2-3 times the risk of developing a melanoma and with more than one first degree relative with melanoma, the incidence is even higher.
Ultraviolet (UV) Light Exposure
Frequent and intense exposure either from sun or artificial indoor tanning beds is a major risk factor for developing melanoma. The more blistering sunburns, particularly before 18 years of age, increases the risk of developing melanoma.
Caucasians are 20% more likely than African Americans to develop melanoma because they do not produce as much pigment to protect them from UV exposure. Fair-skinned, red-haired, blue/green-eyed people have a higher incidence of melanoma.
The number and size moles increases the risk of developing melanoma.
Developing one melanoma increases the risk of developing another melanoma.